Which of the following drugs is NOT commonly associated with DUI offenses?

Caffeine is not commonly associated with DUI offenses primarily because it is a legal stimulant that is widely consumed and does not impair cognitive functions or motor skills to the same extent as the other substances mentioned. While excessive caffeine consumption can lead to jitteriness or anxiety, it typically does not hinder a person's ability to safely operate a vehicle.

In contrast, alcohol, marijuana, and prescription medications can significantly impair judgment, reaction times, and motor coordination, making them more relevant to discussions around DUI offenses. Alcohol is well-known for its debilitating effects on driving capabilities, marijuana can alter perception and coordination, and certain prescription medications may have side effects that impair driving ability. Therefore, caffeine stands out as a substance that is less likely to contribute to DUI incidents.